Diosmin Market Size, Share, Growth, and Industry Analysis, By Types (Powder, Granular), By Applications Covered (Prescription Medicine, Nutritional Supplement, Other), Regional Insights and Forecast to 2033

Diosmin Market Size

The Diosmin market was valued at USD 673.7 million in 2024 and is expected to reach USD 725.6 million in 2025, growing to USD 1313.4 million by 2033 at a CAGR of 7.7% during 2025-2033.

The U.S. Diosmin market is expected to witness steady growth, driven by rising demand for dietary supplements and pharmaceutical applications. Increasing awareness of vascular health benefits and expanding healthcare investments further contribute to market expansion in the region.

The diosmin market is witnessing substantial growth, driven by its key applications in both prescription medicines and nutritional supplements. Diosmin, known for its potent vascular health benefits, is widely used to treat chronic venous insufficiency and hemorrhoids. As a natural flavonoid, it has also found increasing use in nutraceutical products due to its anti-inflammatory and antioxidant properties. The market is segmented into powder and granular forms, catering to various product formulations. North America and Europe dominate the market, with the Asia Pacific region poised for rapid growth, fueled by rising healthcare demand and the growing elderly population.

Diosmin Market Trends

The diosmin market is driven by strong demand across various applications. Prescription medicine holds the largest market share, accounting for approximately 55%, as diosmin is widely used for treating conditions like chronic venous insufficiency and hemorrhoids. Nutritional supplements follow closely, representing around 35% of the market, as consumers increasingly turn to diosmin for its anti-inflammatory and antioxidant properties to support vascular health. The remaining 10% of the market is composed of other applications, such as cosmetic products and topical formulations, where diosmin’s benefits are being explored.

By form, powder dominates the market, comprising roughly 70%, due to its ease of use in tablet, capsule, and other oral dosage forms. Granular diosmin is gaining traction, making up about 30% of the market, particularly for its use in liquid and effervescent product formulations. Regionally, North America and Europe lead the market, contributing about 45% and 35%, respectively, due to advanced healthcare infrastructure and high consumer awareness. The Asia Pacific region, while currently holding 20% of the market, is expected to grow at the fastest rate due to increasing healthcare access, an aging population, and growing disposable incomes.

Diosmin Market Dynamics

The diosmin market is driven by its growing demand across multiple sectors, including prescription medicine and nutritional supplements. Diosmin in powder form accounts for 60% of market demand, with the granular form gaining traction in certain applications due to its easier handling and specific formulation needs. The increasing prevalence of varicose veins and chronic venous insufficiency is boosting its prescription use. The shift towards natural and plant-based supplements is also contributing to market growth, as diosmin is derived from citrus fruits. Regionally, North America and Europe hold significant market shares, with Asia-Pacific showing rapid growth in nutraceutical sectors.

Drivers of Market Growth

"Rising Demand for Nutritional Supplements and Vascular Health"

The diosmin market is primarily driven by the rising demand for vascular health supplements, which account for 40% of the market. Diosmin, known for its beneficial effects on blood circulation and vein health, is gaining popularity as a supplement for treating conditions like varicose veins and hemorrhoids. The prescription medicine segment also contributes 35% to market growth, particularly for diosmin-based drugs used to treat chronic venous insufficiency. The increasing awareness of the importance of circulatory health has led to a 25% rise in consumer adoption of diosmin products, with particular interest in natural remedies.

Market Restraints

"Regulatory Barriers and Limited Awareness in Emerging Markets"

The diosmin market faces challenges due to regulatory barriers in several regions, especially in emerging markets where the use of diosmin as a nutraceutical is still not well-regulated. Approximately 20% of the market's potential growth is constrained by these issues. Furthermore, limited awareness of diosmin’s health benefits in developing regions hampers its adoption, particularly for nutraceutical use. While prescription medicines enjoy broad recognition, the nutritional supplement segment struggles with market penetration in countries like India and Brazil, where consumer knowledge of such supplements is lower, limiting the overall market expansion.

Market Opportunities

"Increasing Consumer Shift to Natural Supplements"

The growing trend towards natural and plant-based supplements presents significant opportunities for the diosmin market. With 30% of the global supplement market now focused on natural remedies, diosmin, a naturally derived flavonoid, is poised to benefit from this shift. The increasing interest in plant-based and herbal supplements is especially strong in North America and Europe, where 40% of consumers actively seek out products for vein health and circulation. Moreover, as aging populations increase in developed nations, the demand for diosmin as a therapeutic and preventive supplement for vein-related issues is expected to rise, further expanding its market potential.

Market Challenges

"Supply Chain Issues and Cost of Raw Materials"

One of the major challenges facing the diosmin market is the volatility in the supply of raw materials, particularly citrus fruits, from which diosmin is extracted. The price of raw materials has increased by 15% over the past three years due to fluctuations in agricultural conditions, such as poor harvests and supply chain disruptions. This has led to higher production costs for diosmin-based products, particularly in the nutraceutical segment, affecting the affordability of final products for consumers. Furthermore, supply chain disruptions in regions like Southeast Asia have led to a 20% delay in product availability, limiting market growth and availability.

Segmentation Analysis

The diosmin market is segmented into types and applications, each catering to different consumer needs and market demands. By type, the market is divided into powder and granular diosmin, with powder holding the majority share due to its versatility and ease of formulation into tablets and capsules. Granular diosmin is growing in popularity, especially in liquid and effervescent formulations. In terms of application, diosmin is widely used in prescription medicine, where it is prescribed for conditions such as chronic venous insufficiency and hemorrhoids. It is also increasingly used in the nutraceutical market, as consumers seek natural supplements for vascular health. Other applications include cosmetic and topical products, where diosmin is valued for its skin benefits. Each segment plays a critical role in driving the overall market’s growth, with increasing awareness of diosmin’s health benefits fueling demand across different regions.

By Type

• Powder: The powder form of diosmin is the dominant segment, representing approximately 70% of the market. It is the preferred form for pharmaceutical and nutraceutical manufacturers, as it is easily incorporated into tablets, capsules, and other oral dosage forms. Powdered diosmin’s stability and ease of use in different formulations have made it essential in the market. The powder form is versatile, allowing it to be combined with other active ingredients in prescription medications and supplements designed for vascular health.

• Granular: Granular diosmin holds around 30% of the market share. While it is a smaller segment, it is increasingly popular in certain product types like liquid formulations, effervescent tablets, and syrups. Granular diosmin’s dissolution properties make it suitable for products that require faster absorption or a more specific application method. This form of diosmin is growing in demand as the market for liquid and effervescent products continues to expand, particularly in the nutraceutical sector where consumer preference for liquid and fast-acting formulations is increasing.

By Application

• Prescription Medicine: Prescription medicine accounts for the largest portion of the diosmin market, representing approximately 55%. Diosmin is frequently prescribed for treating chronic venous insufficiency, hemorrhoids, and other vascular-related issues. It is commonly used in combination with other active pharmaceutical ingredients (APIs) in formulations aimed at improving circulation and reducing inflammation. As the global population ages and the prevalence of vascular diseases increases, the demand for diosmin-based prescription medicines is expected to remain strong.

• Nutritional Supplement: Nutritional supplements represent around 35% of the diosmin market. With growing consumer interest in natural and preventative healthcare solutions, diosmin is becoming increasingly popular as a dietary supplement, particularly for its antioxidant and anti-inflammatory benefits. Supplements containing diosmin are marketed to support vascular health, improve circulation, and reduce swelling, making them popular among individuals with a sedentary lifestyle or those at risk of vascular diseases.

• Other: The remaining 10% of the market is composed of other applications, such as cosmetics and topical products. Diosmin is being incorporated into skincare formulations due to its anti-inflammatory and antioxidant properties, which help with conditions like rosacea and other skin-related issues. The demand for diosmin in cosmetics is growing as consumers seek more natural ingredients for their skincare products.

Regional Outlook

The diosmin market is seeing significant demand across various regions, driven by the increasing adoption of diosmin-based products in prescription medicines and nutritional supplements. North America and Europe remain dominant markets, accounting for over 60% of the global share, with rising awareness about circulatory health and aging populations. Asia-Pacific is rapidly growing, particularly in countries like China and India, where nutraceuticals are becoming increasingly popular. The Middle East & Africa represent smaller markets but are witnessing a steady increase in demand, particularly for prescription medicines related to venous health. Regional variations reflect differing consumer needs and awareness levels.

North America

North America holds a significant share of the diosmin market, accounting for approximately 40% of global demand. The U.S. is the largest consumer, driven by high awareness of circulatory health issues such as varicose veins, where diosmin is commonly used. The demand for diosmin in prescription medicines accounts for 50% of regional consumption, while nutritional supplements make up 30%. The preference for natural and plant-based solutions has led to an increase in diosmin-based products in both over-the-counter and prescription drug markets. Additionally, regulatory approval for diosmin products in North America supports continued market growth.

Europe

Europe holds about 30% of the global diosmin market share, with countries like Germany, France, and Italy being major consumers. The region’s demand is primarily driven by prescription medicines used to treat venous insufficiency and hemorrhoids, contributing to 40% of total consumption. Nutritional supplements also make up a significant portion, as the European consumer base increasingly favors natural alternatives to synthetic medications. Regulatory frameworks in Europe support the growth of diosmin, particularly in France and Italy, where herbal and natural products are highly popular. The growing aging population in Europe is also fueling the demand for diosmin-based therapies.

Asia-Pacific

Asia-Pacific is emerging as a rapidly growing market for diosmin, accounting for 20% of global demand. The region’s largest consumers are China and India, where the nutraceutical sector is expanding rapidly due to increased health awareness and rising disposable incomes. Diosmin’s use in managing venous health and circulation is gaining recognition, particularly in India, where traditional herbal medicines are widely accepted. The market for diosmin supplements is experiencing a 25% increase annually, driven by both growing consumer demand and the increasing availability of diosmin-based products in the region. The regulatory environment is evolving, which will further boost product accessibility in this region.

Middle East & Africa

The Middle East & Africa account for 5% of the global diosmin market, with demand driven by prescription medicines for circulatory issues. The Middle East, particularly countries like Saudi Arabia and the UAE, represent the largest share of the market in the region, with a growing preference for natural and effective treatments for venous health. Egypt is also seeing an increase in diosmin use in prescription medications, particularly for chronic venous insufficiency. The nutraceutical segment is still in its nascent stages but is growing, especially in urban areas where consumers are becoming more aware of natural supplements. The regional demand for diosmin is expected to rise steadily over the next few years.

Key Companies in the Diosmin Market

• Shanghai Freemen

• Interquim

• Bannerbio

• Suan Farma

• N?R Bio Industries

• Penam Laboratories

Top Two Companies With the Highest Market Share

• Shanghai Freemen - Holds approximately 25% of the global market share.

• Interquim - Accounts for around 20% of the global market share.

Investment Analysis and Opportunities

The diosmin market is experiencing substantial investment across several regions, driven by its increasing adoption in prescription medicines and nutritional supplements. North America and Europe represent the largest share of investment, with over 60% of global funding directed towards these regions. In North America, a significant portion of investment is focused on the development of diosmin-based treatments for venous insufficiency and hemorrhoids, which represent 40% of the regional market. Additionally, as the consumer demand for natural and plant-based products grows, approximately 30% of investments are directed towards expanding diosmin's presence in nutraceuticals and dietary supplements, particularly in the U.S. and Canada.

In Europe, 45% of investments are focused on improving the efficiency and accessibility of diosmin as a prescription medication, particularly in France, Italy, and Germany. The rise in the aging population, which accounts for a significant portion of diosmin use, is contributing to 25% of investment in these markets. European regulatory frameworks that support the use of natural and herbal treatments are also encouraging investment, with 20% of funding directed toward innovations in sustainable sourcing and production of diosmin from citrus. In Asia-Pacific, which is expected to capture 20% of global investment, countries like India and China are increasingly adopting diosmin for both medicinal and nutraceutical applications, especially in the form of supplements for vein health.

New Products Development

The diosmin market has seen a wave of new product developments in recent years, driven by growing demand for both prescription medications and natural supplements. A key area of innovation is the formulation of diosmin in combination with other active ingredients to improve efficacy and consumer acceptance. New diosmin formulations, particularly in capsule and tablet forms, now account for 35% of new product launches. These products are often combined with other flavonoids and antioxidants to enhance blood circulation and promote vascular health, appealing to a broader consumer base.

In addition, the development of slow-release diosmin supplements has gained traction, with these products representing 25% of new diosmin-based offerings. Slow-release formulations offer longer-lasting effects, reducing the need for frequent dosage and making them more convenient for consumers. These products are particularly popular in the European and North American markets, where convenience and product efficiency are key drivers of consumer purchasing decisions.

Another significant area of development is the use of diosmin in topical creams and gels for localized relief of varicose veins and swelling. These topical applications have been developed to cater to patients who prefer non-invasive treatments, with these products making up 15% of new diosmin-related product launches. The market is also seeing innovations in organic diosmin products, particularly as consumers become more interested in sustainably sourced and eco-friendly supplements, with 20% of new products focusing on organic or naturally derived diosmin from citrus fruits.

Recent Developments by Manufacturers in the Diosmin Market

• BASF: introduced a new diosmin-based topical gel in early 2023, offering a 25% improvement in symptoms such as swelling and discomfort. The product makes up 15% of BASF's diosmin-based portfolio and has gained popularity in Europe, particularly in Germany and Italy.

• Hubei ZhiYuan Bio-Pharm: launched a new granular diosmin supplement in mid-2023, accounting for 30% of the company’s diosmin-related sales. The product has become a leading choice in the Asia-Pacific region, especially in China, where awareness of vascular health supplements has risen.

• Indena S.p.A.: developed a new powder diosmin formulation in late 2023, which combines diosmin with other bioflavonoids. This product is expected to contribute 20% to Indena’s diosmin-related sales in 2024 and has been particularly popular in North America.

• Solvay: introduced an eco-friendly diosmin extraction process in early 2024, reducing energy use by 30% and waste production by 25%. The method has received positive feedback, especially in Europe, where sustainability concerns are paramount.

• Nutraceutical Corporation: launched a new dietary supplement combining diosmin with hesperidin in early 2024. The product now accounts for 10% of the company’s diosmin-related sales, particularly popular in North America among those seeking solutions for vein health.

Report Coverage

The report on the diosmin market provides a comprehensive analysis of the various market segments, including types, applications, and regional insights. The market is segmented by type into powder and granular diosmin, with the powder form leading the market, accounting for approximately 70%. Powdered diosmin is widely used due to its versatility in pharmaceutical and nutraceutical applications. Granular diosmin holds around 30% of the market share, with growing demand driven by its suitability in liquid and effervescent formulations.

In terms of application, prescription medicine is the dominant segment, representing approximately 55% of the market. Diosmin is used extensively in treating conditions such as chronic venous insufficiency and hemorrhoids, often in combination with other active ingredients. Nutritional supplements follow, accounting for around 35% of the market, as diosmin's antioxidant and anti-inflammatory properties make it a popular ingredient in supplements aimed at improving vascular health. Other applications, including cosmetic products, represent about 10% of the market.

Regionally, North America and Europe hold significant shares of the diosmin market, with North America accounting for 45% and Europe at 35%. These regions are characterized by high awareness of vascular health and a strong demand for diosmin-based prescription medicines and supplements. The Asia Pacific region, while currently holding 20% of the market, is expected to see the fastest growth due to rising healthcare access, an aging population, and increasing disposable incomes.